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Title:
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Muscarinic MI and Glutamate Receptor Gene Expression and their Functional Role in Pilocarpine Induced Temporal Lobe Epilepsy in rats: Regulation by Bacoside A and Bacopa monnieri Extracts |
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Author:
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Reas Khan, S; Dr. Paulose, C S
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Abstract:
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The present work is to understand the alterations of total muscarinic.
muscarinic MI and glutamate receptors in the brain regions of pilocarpine induced
epileptic rats. The work focuses on the evaluation of the anti epileptic activity of
extracts of Bacopa monnieri, Bacoside A and Carbamazepine in vivo. The
molecular changes in the muscarinic M I receptors in the pre- and post-treated
epileptic model with Bacopa monnieri, Bacoside A and Carbamazepine were also
studied. These studies will help us to elucidate the functional role of muscarinic
and glutamate receptors in epilepsy. |
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Description:
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Department of Biotechnology, Cochin University of
Science and Technology |
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URI:
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http://dyuthi.cusat.ac.in/purl/2802
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Date:
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2007-04 |