Jayesh, P; Dr.Bright Singh,I S(Cochin University of Science and Technology, September , 2012)
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Abstract:
Unveiling the molecular and regulatory mechanisms that prevent in vitro
transformation in shrimp remains elusive in the development of continuous cell
lines, with an arduous history of over 25 years (Jayesh et al., 2012). Despite
presenting challenges to researchers in developing a cell line, the billion dollar
aquaculture industry is under viral threat. In addition, the regulatory mechanisms
that prevent in vitro transformation and carcinoma in shrimps might provide new
leads for the development of anti-ageing and anti-cancer interventions in human
(Vogt, 2011) and in higher vertebrates. This highlights the importance of
developing shrimp cell lines, to bring out effective prophylactics against shrimp
viruses and for understanding the mechanism that induce cancer and ageing in
human.. Advances in molecular biology and various gene transfer technologies for
immortalization of cells have resulted in the development of hundreds of cell lines
from insects and mammals, but yet not a single cell line has been developed from
shrimp and other marine invertebrates. With this backdrop, the research described
in this thesis attempted to develop molecular tools for induced in vitro
transformation in lymphoid cells from Penaeus monodon and for the development
of continuous cell lines using conventional and novel technologies to address the
problems at cellular and molecular level.
Description:
National Centre for Aquatic Animal
Health, School of Environmental Studies, Cochin University of Science and
Technology
Sobhana, Mathew; Dr.Girish Kumar, K(Cochin University of Science and Technology, March , 2012)
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Abstract:
Electroanalytical techniques represent a class of powerful and versatile
analytical method which is based on the electrical properties of a solution of
the analyte when it is made part of an electrochemical cell. They offer high
sensitivity, accuracy, precision and a large linear dynamic range. The cost of
instrumentation is relatively low compared to other instrumental methods of
analysis. Many solid state electrochemical sensors have been commercialised
nowadays. Potentiometry is a very simple electroanalytical technique with
extraordinary analytical capabilities. Since valinomycin was introduced as an
ionophore for K+, Ion Selective Electrodes have become one of the best
studied and understood analytical devices. It can be used for the
determination of substances ranging from simple inorganic ions to complex
organic molecules. It is a very attractive option owing to the wide range of
applications and ease of the use of the instruments employed. They also
possess the advantages of short response time, high selectivity and very low
detection limits. Moreover, analysis by these electrodes is non-destructive and
adaptable to small sample volumes. It has become a standard technique for
medical researchers, biologists, geologists and environmental specialists.
This thesis presents the synthesis and characterisation of five
ionophores. Based on these ionophores, nine potentiometric sensors are
fabricated for the determination of ions such as Pb2+, Mn2+, Ni2+, Cu2+ and
Sal- ion (Salicylate ion). The electrochemical characterisation and analytical
application studies of the developed sensors are also described. The thesis is
divided into eight chapters
Description:
Department of Applied Chemistry, Cochin University of Science and Technology
Manju, N J; Dr.Bright Singh,I S(Cochin University of Science and Technology, October , 2007)
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Abstract:
This thesis entitled Development of nitrifying ans photosynthetic sulfur bacteria based bioaugmentation systems for the bioremediation of ammonia and hydregen sulphide in shrimp culture.
the thesis is to propose a sustainable, low cost option for the mitigation of toxic ammonia and hydrogen sulphide in shrimp culture systems. Use of ‘bioaugmentors’ as pond additives is an emerging field in aquaculture. Understanding the role of organisms involved in the ‘bioaugmentor’ will obviously help to optimize conditions for their activity.The thesis describes the use of wood powder immobilization of nitrifying consortia.Shrimp grow out systems are specialized and highly dynamic aquaculture production units which when operated under zero exchange mode require bioremediation of ammonia, nitrite nitrogen and hydrogen sulphide to protect the crop. The research conducted here is to develop an economically viable and user friendly technology for addressing the above problem. The nitrifying bacterial consortia (NBC) generated earlier (Achuthan et al., 2006) were used for developing the technology.Clear demonstration of better quality of immobilized nitrifiers generated in this study for field application.
Description:
National Centre for Aquatic Animal Health, School of Environmental
Studies, Cochin University of Science and Technology
Bright Singh, I S; Rosamma, Philip; Cini, Achuthan; Rejish Kumar, V J; Manju, N J(New Delhi, Council of Scientific & Industrial Research., April 17, 2006)
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Abstract:
Two ammonia oxidizing (AMOPCU-1 and AMONPCU-1) and two nitrite oxidizing (NIOPCU-1 and NIONPCU-1) consortia for activating nitrifying bioreactors and thereby establishing nitrification in penaeid and non-penaeid hatchery systems were developed by enrichment. For further amplification of the consortia a simple medium having seawater (either salinity 30 ‰ or 15 ‰) as base, supplemented with NH4+-N/NO2--N and PO4- and pH adjusted to 8 was identified. During the amplification in a fermentor the consortia exhibited excessive wall growth and diminished their yield coefficient posing difficulty in harvesting the cells completely. The consortia consisted of both Gram negative and Gram-positive bacterial cells embedded in a mucilaginous matrix of glycocalyx - like material presumably composed of polysaccharides. The consortia besides being useful in activating nitrifying bioreactors developed for shrimp/prawn hatchery systems can also be used as bioaugmentors in the bioremediation of ammonia and nitrite toxicity in aquaculture systems.
Description:
Indian Journal of Marine Sciences
Vol. 35(3), September 2006, pp. 240-248
Jaya, V.L; Dr Gopika Kumari(Cochin University of Science and Technology, May 20, 2015)
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Abstract:
Digital Image Processing is a rapidly evolving eld with growing applications
in Science and Engineering. It involves changing the nature
of an image in order to either improve its pictorial information
for human interpretation or render it more suitable for autonomous
machine perception. One of the major areas of image processing
for human vision applications is image enhancement. The principal
goal of image enhancement is to improve visual quality of an image,
typically by taking advantage of the response of human visual
system.
Image enhancement methods are carried out usually in the pixel
domain. Transform domain methods can often provide another way
to interpret and understand image contents. A suitable transform,
thus selected, should have less computational complexity. Sequency
ordered arrangement of unique MRT (Mapped Real Transform)
coe cients can give rise to an integer-to-integer transform, named
Sequency based unique MRT (SMRT), suitable for image processing
applications. The development of the SMRT from UMRT (Unique
MRT), forward & inverse SMRT algorithms and the basis functions
are introduced. A few properties of the SMRT are explored and its
scope in lossless text compression is presented.
Neetha,John; Dr.Rani,Joseph(Cochin University of Science and Technology, December 30, 1998)
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Abstract:
Novel latex based and solution based adhesives were prepared and evaluated for wood to wood bonding.These adhesive were found to be superior to commercical adhesives like fevicol and dentrite.Novel adhesives were prepared for leather to leather bonding and these were also found to be more efficientt than the polyurethane type and dentrite adhesives used commercially.A novel strip adhesive system employing very low amount of solvents was tried successfully for rubber-to-metal bonding.Further ,a novel adhesive system was investigated successfully for bonding copper coated bead wire and steel cord to rubber by modifying it with chloroprene rubber.
Description:
Department of Polymer Science and Rubber Technology, Cochin
University of Science and Technology
Suma, K K; Dr.Rani,Joseph(Cochin University of Science and Technology, July , 2009)
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Abstract:
The present study describes the preparation of Vinyl acetate-Butyl
acrylate copolymer lattices of varying compositions and solid contents by
semicontinuous emulsion polymerization method. This copolymer lattices were
used as binder to develop a new surface coating formulation. The properties of
this surface coating were improved by using nano TiO2 colloidal sol as a
pigment. Antimicrobial activity of surface coatings was improved by the
addition of carboxymethyl chitosan as biocide. Uniformly dispersed tyre crumb
was used to give a mat finish to the coating. The mechanical properties adhesive
properties, thermal properties etc. of the coatings are presented in thesis.
Description:
Dept. of Polymer Science and Rubber Technology,
Cochin University of Science and technology
Benjamin Varghese, P; Dr.Madhusoodanan, K N(Cochin University Of Science And Technology, February 15, 2013)
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Abstract:
The objective of the preset work is to develop optical fiber
sensors for various physical and chemical parameters. As a part of this
we initially investigated trace analysis of silica, ammonia, iron and
phosphate in water. For this purpose the author has implemented a dual
wavelength probing scheme which has many advantages over
conventional evanescent wave sensors. Dual wavelength probing
makes the design more reliable and repeatable and this design makes
the sensor employable for concentration, chemical content,
adulteration level, monitoring and control in industries or any such
needy environments. Use of low cost components makes the system
cost effective and simple. The Dual wavelength probing scheme is
employed for the trace analysis of silica, iron, phosphate, and
ammonia in water. Such sensors can be employed for the steam and
water quality analysers in power plants. Few samples from a power
plant are collected and checked the performance of developed system
for practical applications.
Description:
Department of Instrumentation,
Cochin University of Science and Technology
Kishore,V C; Dr.Sudha Kartha,C; Dr. Sreekumar, K(Cochin University of Science & Technology, June , 2008)
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Abstract:
This Thesis discussed molecules suitable for photorefractive effect. Out
of the molecules studied, only one system was used to make photorefractive polymers system. Other molecules, especially, the electro-optic
polymer, Poly(3-methacrloyl-1-(4'-nitro-4-azo-1'-phenyl)phenylalanine-co-
methyl methacrylate) can be subjected to more detailed studies to explore
the possibilities of using them for electro-optic applications. Though not included in the thesis, the efficient photoconductor, Poly(6-tert-butyl-3-
phenyl-3,4-dihydro-2H-1,3-benzoxazine) sensitized with C60, which was described in Chapter 3 showed a low magnitude photovoltaic effect. This
hints at the possibility of using this system for organic solar cells also. The thesis presented the initial observation of photorefractive effect in
a polybenzoxazine based polymer system. A detailed analysis of the effect of C60, ECZ and DR1 can be carried out to check for the possibility of a high efficiency photorefractive system.
Description:
Applied Optics Division, Department of Physics, Cochin University of Science and Technology
Jaya, S; Dr. Ramakrishna, S V(Cochin University Of Science And Technology, August 19, 1999)
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Abstract:
P rosea syn. Indica belong to the family of plumbaginaceae, is an
important medicinal plant, cultivated widely in India. The roots of these
plant are generally used for medicinal purposes mainly as diuretic,
germicidal, vessicant, and abortifacient. It is also used for anaemia,
diarrhea, leprosy and common wart. The bark of the root contains orange
yellow pigment named plumbagin, a crystalline substance, belongs to the
class of naphthoquinone. Its chemical structure is 5-hydroxy 2-methyl 1,4naphthoquinone. Apart from P rosea, P zeylanica, P europea, Drosera
and Drosophyllum also contains plumbagin. The most exploited source of
plumbagin is, of course, P. rosea roots. The roots contain O.9mg/ g D.Wt. of
plumbagin in the roots. These plants grow very slowly and the roots suitable
for plumbagin extraction can be obtained only after several years of growth.
The productivity of the plant is also rather poor. The focus of the present study was to develop alternative strategies to obtain plumbagin. The tissue culture of P rosea for micropropagation has been studied
Description:
Department Of Biotechnology,Cochin University Of Science And Technology
Rani, Joseph(John Wiley & Sons, Inc., February 16, 1999)
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Abstract:
Microcellular (MC) soles based on polybutadiene (BR) and low-density
polyethylene (LDPE) blends for low-temperature applications were developed. A part of
BR in BR-LDPE blend was replaced by natural rubber (NR) for property improvement.
The BR-NR-LDPE blend-based MC sole shows good technical properties. Sulphur
curing and DCP curing were tried in BR-LDPE and NR-BR-LDPE blends. Study
shows that sulphur-cured MC sheets possess better technical properties than DCPcured
MC sheets. 90/10 BR-LDPE and 60/30/10 BR-NR-LDPE blend combinations are
found to be suitable for low-temperature applications.
Priya, Viswanath; Dr. Eby Thomas, Thachil(Cochin University of Science and Technology, September , 2007)
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Abstract:
Research in the field of polymer modified cement has been carried out for
the last 70 years or more. Polymers are mostly used to enhance durability and
sustainability of cement concrete and in combination with classical construction
materials a synergistic effect is obtained. In this work different polymers were
added to Portland cement in various proportions and the mechanical and
chemical resistance properties of the resultant composites when exposed to
chemical environments were studied. Microstructural studies were also carried
out to investigate the morphology of the composite and analyse the nature of
interactions taking place between the cement and polymer phases. Though most
polymers did not improve the compressive strength of the cement paste, it was
found that they enhanced the resistance of the virgin cement paste to external
chemical environments. The polymers seal the pores in the cement matrix and
bridge the microcracks within the composite. Some of the polymers underwent
chemical interactions with the cement paste thereby interfering in the hydration
of cement. Polymers also decreased the leachability of water soluble components
of virgin cement resulting in composites having improved durability. An attempt
to correlate the structure of the polymers with the properties of the resultant
composites is also presented.
Description:
Department of
Polymer Science and Rubber Technology, Cochin University of
Science and Technology
Sanal, K C; Dr.Jayaraj, M K(Cochin University of Science And Technology, January 27, 2014)
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Abstract:
Semiconductor physics has developed significantly in the field of re-
search and industry in the past few decades due to it’s numerous
practical applications. One of the relevant fields of current interest in
material science is the fundamental aspects and applications of semi-
conducting transparent thin films. Transparent conductors show the
properties of transparency and conductivity simultaneously. As far
as the band structure is concerned, the combination of the these two
properties in the same material is contradictory. Generally a trans-
parent material is an insulator having completely filled valence and
empty conduction bands. Metallic conductivity come out when the
Fermi level lies within a band with a large density of states to provide
high carrier concentration. Effective transparent conductors must nec-
essarily represent a compromise between a better transmission within the visible spectral range and a controlled but useful electrical con-
ductivity [1–6]. Generally oxides like In2O3, SnO2, ZnO, CdO etc,
show such a combination. These materials without any doping are
insulators with optical band gap of about 3 eV. To become a trans-
parent conductor, these materials must be degenerately doped to lift
the Fermi level up into the conduction band. Degenerate doping pro-
vides high mobility of extra carriers and low optical absorption. The
increase in conductivity involves an increase in either carrier concen-
tration or mobility. Increase in carrier concentration will enhance the
absorption in the visible region while increase in mobility has no re-
verse effect on optical properties. Therefore the focus of research for
new transparent conducting oxide (TCO) materials is on developing
materials with higher carrier mobilities.
Description:
Department of Physics
Cochin University of Science and Technology