Anuja, E V; Girish Kumar, K(Cochin University Of Science And Technology, August 6, 2015)
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Abstract:
There is an enormous demand for chemical sensors in many areas and disciplines including chemistry, biology, clinical analysis, environmental science. Chemical sensing refers to the continuous monitoring of the presence of chemical species and is a rapidly developing field of science and technology. They are analytical devices which transform chemical information generating from a reaction of the analyte into an measurable signal. Due to their high selectivity, sensitivity, fast response and low cost, electrochemical and fluorescent sensors have attracted great interest among the researchers in various fields.
Development of four electrochemical sensors and three fluorescent sensors for food additives and neurotransmitters are presented in the thesis. Based on the excellent properties of multi walled carbon nanotube (MWCNT), poly (L-cysteine) and gold nanoparticles (AuNP) four voltammetric sensors were developed for various food additives like propyl gallate, allura red and sunset yellow. Nanosized fluorescent probes including gold nanoclusters (AuNCs) and CdS quantum dots (QDs) were used for the fluorescent sensing of butylated hydroxyanisole, dopamine and norepinephrine.
A total of seven sensors including four electrochemical sensors and three fluorescence sensors have been developed for food additives and neurotransmitters.
Laina, A L; Dr.Girish Kumar, K(Cochin University Of Science And Technology, April , 2013)
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Abstract:
Electrochemical sensors are increasingly being investigated to perform
measurements for single or multiple analytes. Demanded by modern medical
diagnosis, advances in microfabrication technology have led to the development
of fast, sensitive and selective electrochemical sensors for drug analysis.
Electrochemical sensors for the measurement of analytes of interest in clinical
chemistry are ideally suited for these applications, due to their high sensitivity
and selectivity, simple-to-operate, rapid response time and low-cost.
As part of the present investigations eight voltammetric sensors have been
fabricated for six drugs such as PAM Chloride, Tamsulosin Hydrochloride,
Hesperidin Methyl Chalcone, Guaiphenesin, Cephalexin and Amoxicillin
trihydrate. The modification techniques adopted as part of the present work
include multiwalled carbon nanotube (MWNT) based modifications,
electropolymerization, gold nanoparticle (AuNP) based modifications and
platinum nanoparticle (PtNP) based modifications.
The thesis is divided into nine chapters
Description:
Department of Applied Chemistry
Cochin University of Science and Technology