| dc.contributor.author |
Paulose,C S |
|
| dc.contributor.author |
Dakshinamurti,K |
|
| dc.date.accessioned |
2008-08-14T06:47:39Z |
|
| dc.date.available |
2008-08-14T06:47:39Z |
|
| dc.date.issued |
1984-04-24 |
|
| dc.identifier.uri |
http://dyuthi.cusat.ac.in/purl/655 |
|
| dc.description.abstract |
The high-affinity of [3H]y-aminobutyric acid (GABA) to GABAA receptors and [3H]baclofen to
GABAB receptors were studied in the cerebellum of pyridoxine-deficient rats and compared to
pyridoxine-supplemented controls. There was a significant increase in the maximal binding ( Bmax) of both
GABAA and GABAB receptors with no significant difference in their binding affinities (Kd). The changes
observed suggest a supersensitivity of GABAA and GABAB receptors which seems to correlate negatively
with the concentration of GABA in the cerebellum of pyridoxine-deficient rats. |
en_US |
| dc.language.iso |
en |
en_US |
| dc.publisher |
Department of Biotechnology |
en_US |
| dc.subject |
GABA receptor |
en_US |
| dc.subject |
GABA binding |
en_US |
| dc.subject |
GABAA receptor |
en_US |
| dc.subject |
GABAB receptor |
en_US |
| dc.title |
Enhancement Of High Affinity Y-Aminobutyric Acid Receptor Binding In Cerebellum Of Pyridoxine-Deficient Rat |
en_US |
| dc.type |
Working Paper |
en_US |