Neurotransmitter Functional Role in Neurodegenerative Diseases: human Health

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Neurotransmitter Functional Role in Neurodegenerative Diseases: human Health

Show simple item record Paulose,C S Amee,Krishnakumar Anu, Joseph 2008-08-13T09:18:06Z 2008-08-13T09:18:06Z 2007
dc.description.abstract Neuroscience is the study of'tbe ne rvous system , including the i - ; . in, spinal cord and peripheral nerves . Neurons are the basic cells of the brain and nervous system which exerts its functional role through various neurotransmitters and receptor systems . The activity of a nen ren depends on the balance between the number of excitatory and inhibito r y processes affecting it, both processes occurring individually and sin ,tlte-' ,ieously. The functional bal,ince of different neurotransmitters such as Acct >>lcholine (Ach), Dopamine (DA), Serotonin (5-1-17), Nor epinepbri,te (N.1 j, Epinephrine (LPI), Glutamate and Gamma amino butyric acid (GA BA) regulates the growth , division and other vital functions ofa normal cell / organisin (Sudha, 1 998). The micro-environ ; nertt of the cell is controlled / the macro-environment that surrounds the individual. Any change in the cell environment causes imbalance in cell homeostasis and f,ntction. Pollution is a significant cause of imbalance caused iii the inacYcenvironment. Interaction with polluted environments can have an adverse impact on the health of humans. The alarming rise in enviromilmieil cont.iniin :rtion has been linked to rises in levels of pesticides, ndltstr al effluents, domestic Waste, car exhausts and other anthropogenic activities. Persistent exposures to contaminant cause a negative imp,-, on brain health and development . Pollution also causes a change in the neurotransmitters and their receptor function leading to earl.;' recurrence of neurodcge,terative disorders such as flypoxia , Alzbeimers's and Huntington 's disease early in life. en_US
dc.language.iso en en_US
dc.publisher Department of Biotechnology en_US
dc.subject Neurotransmitters en_US
dc.subject neurological disorders en_US
dc.subject Environment en_US
dc.subject Pollution en_US
dc.title Neurotransmitter Functional Role in Neurodegenerative Diseases: human Health en_US
dc.type Working Paper en_US

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