Hypoglycaemic Effect of Alkaloids Preparation From Leaves of Aegle Marmelose

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Hypoglycaemic Effect of Alkaloids Preparation From Leaves of Aegle Marmelose

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Title: Hypoglycaemic Effect of Alkaloids Preparation From Leaves of Aegle Marmelose
Author: Ponnachan,P T C; Paulose,C S; Panikkar,K R
Abstract: Alloxan induced diabetic animal model was used to evaluate the antidiabetic effect of alkaloids extracted from the leaves of Aegis marine/ose. The alkaloid extract maintained the weight of animals near to that of control ones - whereas there was a decrease in the body weight of diabetic animals. A significant increase in blood glucose (342. 14 -+- 14.89 mg/dl) was seen in diabetic animals but in alkaloid treated group the blood glucose was lowered (90: 12 +_5.81 mg/dl). There was no decrease in blood urea arid sreum cholesterol in the alkaloid treated group of diabetic animals. The liver glycogen decreased in diabetic animals (1.27+.12 g/100g of wet tissue) and the treatment brought the glycogen level to that of control ones (2.51 +.75 g/100 g of wet tissue). The result show that the alkaloid extract has hypoglycaemic activity.
URI: http://dyuthi.cusat.ac.in/purl/585
Date: 1993


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