Establishment of Shrimp Cell Lines: Perception and Orientation

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Establishment of Shrimp Cell Lines: Perception and Orientation

Show simple item record Bright Singh, I S Jose, Seena Jayesh, P 2014-07-16T06:34:06Z 2014-07-16T06:34:06Z 2012-08-14
dc.description Indian J. Virol. (July–September 2012) 23(2):244–251 DOI 10.1007/s13337-012-0089-9 en_US
dc.description.abstract Development of continuous shrimp cell lines for effective investigation on shrimp viruses remains elusive with an arduous history of over 25 years. Despite presenting challenges to researchers in developing a cell line, the billion dollar aquaculture industry is under viral threat. Advances in molecular biology and various gene transfer technologies for immortalization of cells have resulted in the development of hundreds of cell lines from insects and mammals, but yet not a single cell line has been developed from shrimp and other marine invertebrates. Though improved growth and longevity of shrimp cells in vitro could be achieved by using modified growth media this did not make any leap to spontaneous transformation; probably due to the fact that shrimp cells inhibited neoplastic transformations. Oncogenic induction and immortalization are considered as the possible ways, and an exclusive medium for shrimp cell culture and an appropriate mode of transformation are crucial. In this review status of shrimp cell line development and its future orientation are discussed en_US
dc.description.sponsorship Cochin University of Science and Technology en_US
dc.language.iso en en_US
dc.publisher Springer en_US
dc.subject Shrimp cell culture en_US
dc.subject Culture medium en_US
dc.subject Cell line en_US
dc.subject Transformation en_US
dc.subject Transduction en_US
dc.subject Immortalization en_US
dc.title Establishment of Shrimp Cell Lines: Perception and Orientation en_US
dc.type Article en_US

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