Bijina, B; Dr.Chandrasekaran,M(Cochin University of Science & Technology, May , 2006)
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Abstract:
Protease inhibitors are one of the most important tools of nature for
regulating the proteolytic activity of their target proteases. They are
synthesized in biological systems and they play a critical role in controlling
a number of diverse physiological functions. The current investigation
focused on the isolation, purification and characterization of a novel
protease inhibitor from Moringa oleifera. The results obtained during the
course of study opens new perspectives for the utilization of protease
inhibitor from Moringa oleifera for various pharmaceutical, agricultural and
food industries. The biological and physicochemical properties exhibited by
the novel protease inhibitor from Moringa oleifera clearly testify its
suitability for the development as a drug for application in pharmaceutical
industries such as anticoagulant agent or biocontrol agent in agriculture and
even as a food preservant. There is a scope for further research on the
structure elucidation and protein engineering towards a wide range of
further applications. Detailed structure/function analysis of these proteins is
important to facilitate their use in genetic engineering for various
applications.
Description:
Department of Biotechnology,
Cocbin University of Science and Technology