Leena, R; Dr.Girish Kumar, K(Cochin University Of Science And Technology, October 31, 2012)
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Abstract:
Voltammetric methods are applicable for the determination of a wide
variety of both organic and inorganic species. Its features are compact
equipment, simple sample preparation, short analysis time, high accuracy and
sensitivity. Voltammetry is especially suitable for laboratories in which only a
few parameters have to be monitored with a moderate sample throughput. Of
various electrode materials, glassy carbon electrode is particularly useful
because of its high electrical conductivity, impermeability to gases, high
chemical resistance, reasonable mechanical and dimensional stability and
widest potential range of all carbonaceous electrodes. Electrode modification
is a vigorous research area by which the electrochemical determination of
various analyte species is facilitated. The scope of pharmaceutical analysis
includes the analytical investigation of pure drug, drug formulations,
impurities and degradation products of drugs, biological samples containing
the drugs and their metabolites with the aim of obtaining data that can
contribute to the maximal efficacy and maximal safety of drug therapy.
This thesis presents the modification of glassy carbon electrode using
metalloporphyrin and dyes and subsequently using these modified electrodes
for the determination of various pharmaceuticals. The thesis consists of 9
chapters.
Description:
Department of Applied Chemistry
Cochin University of Science and Technology
Balachandran, K K; Sankaranarayanan, V N(National Institute of Oceanography, 2001)
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Abstract:
The present study is an attempt to understand some of the chemical oceanographic processes of the coastal water and the backwaters of Cochin. The importance of this study lies in the fact that there has been an increasing concern on the environmental degradation of Cochin backwaters with respect to water and sediments due to various anthropogenic activities. The study comprises the results and discussion of the hydro chemical parameters of coastal waters of Cochin during different seasons with statistical analysis. The parameters dealt with are salinity, temperature, pH, dissolved oxygen, nitrite-N, nitrate-N, ammonia-N, Silicate-Si, phosphate-P, chlorophyll ‘a’ and suspended solids, dissolved trace metals and sediment characteristics including sediment metals
Renjith, K R; Dr.Chandramohanakumar, N(Cochin University of Science and Technology, December , 2006)
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Abstract:
The amplified human role in shaping natural processes makes it imperative to understand the interactions between abiotic and biotic processes, whcih pertain particularly to the most dyanamic aboitic factor,water. The assessment of environmental parameters is indispensable for the sustainable management of the aqutic system .The conscious harnessing and pampering to protect the characteristics of the ecosystems is the of the day.This thesis attempts to characterize the chemical dynamacity of a tropical estury in relation to the bio, geo and physical processes and thereby to propose a management scheme for its sustainability. Micro speciation is used as a tool for this.
Chandrasegaran, K; Dr.Sebastian, V D(Cochin University of Science and Technology, December 12, 1996)
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Abstract:
This thesis entitled “Child labour in india”Children are "supremely important assets" of the nation, India proudly asserts in the National Policy for Children (1974) gracefully acknowledging that they are future citizens on whose shoulders the destiny of our nation rests.Childhood is a time of discovery as the world and all it contains are new to children. It is a time of excitement and anticipation. lt is a time of dreams and fantasies. And it is a time of receiving love and appreciation. Paradoxically, a picture of contrast is a common experience in India as a vast majority of children who are starved of basic needs of nutrition, health and education are made to work at an early age in exploitative conditions. The specter of child labour is a glaring anomaly in a country graciously adorning human right. In an exposition of the problem involving human rights abuse, Chapters from Two to Five of this study have shot into focus the human rights jurisprudence with special reference to the rights of children. Children have a particular identity as children and they also have a universal identity as human beings.The concern for mankind expressed unequivocally and transcending the globe will be real and moving and not mere rhetoric and ritual if and only when it begins with children, as, to quote the words of Nehru, the human being counts much more as a child than as a grown up.The first three of these rights namely right to health, right to nutritive food and right to education are dealt with in Chapter Four. Finally, the positive effects of education have been sketched in that chapter to impress upon its significance in the development of human capitals.legitimization. The theme of legitimacy was rationalised on the ground of poverty as a strategy for achieving eradication of child labour ultimately by enforcing minimum wages, shorter working hours, leave compensation, non-formal education etc., as the employer would soon discover that child labour is not cheap and would be obliged to substitute adult labour. However, humanising the work life is only a promise to the detriment of children as the Act of 1986 enacted as a part of the new strategy is nearingcompletion of a decade of existence but nowhere near the fulfilment of the mission.As similar urge is more necessary and overdue, it has been suggested that a special body be established with all powers for cognisance of human rights abuse of children.It is proposed to conclude this study with a brief summary of the inferences drawn from the foregoing chapters along with a few suggestions emerging out of those inferences
Description:
School of Legal Studies, Cochin University of
Science and Technology
Suresh, P V; Dr.Chandrasekaran,M(Cochin University of Science and Technology, October 10, 1996)
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Abstract:
In this thesis an attempt is made to explore the potential of marine fungi for the production of chitinolytic enzymes and to recognize the ability to hydrolyse native chitin through submerged as well as solid substrate fermentation culture conditions, using wheat bran and shellfish processing waste such as ‘prawn waste’ as solid substrates. Attempt was made to isolate a potential chitinase producing fungus from marine environment and to develop an ideal bioprocess for the
production ofchitolytic enzymes.Present study indicate scope for utilization of B. bassiana
for industrial production of chitinase using prawn waste as solid substrate employing solid substrate fermentation.
Description:
Department of Biotechnology. Cochin University of Science and Technology
Chinthu, Romeo; Dr. Paulose, C S(Cochin University of Science and Technology, August 17, 2012)
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Abstract:
The present study deals with the Cholinergic Receptor subtypes functional regulation in spinal cord injured monoplegic rats: Effect of 5-HT GABA and bone marrow cells.Spinal cord injury causes permanent and irrevocable motor deficits and neurodegeneration. Disruption of the spinal cord leads to diminished transmission of descending control from the brain to motor neurons and ascending sensory information. Behavioural studies showed deficits in motor control and coordination in SCI rats. Cholinergic system plays an important role in SCI, the evaluation of which provides valuable insight on the underlying mechanisms of motor deficit that occur during SCI. The cholinergic transmission was studied by assessing the muscarinic and nicotinic receptors; cholinergic enzymes- ChAT and AChE; second messenger enzyme PLC; transcription factor CREB and second messengers - IP3, cAMP and cGMP. We observed a decrease in the cholinergic transmission in the brain and spinal cord of SCI rats. The disrupted cholinergic system is the indicative of motor deficit and neuronal degeneration in the spinal cord and brain regions. SCI mediated oxidative stress and apoptosis leads to neuronal degeneration in SCI rats. The decreased expression of anti oxidant enzymes – SOD, GPx and neuronal cell survival factors - BDNF, GDNF, IGF-1, Akt and cyclin D2 along with increased expression of apoptotic factors – Bax, caspase-8, TNFa and NF-kB augmented the neuronal degeneration in SCI condition. BMC administration in combination with 5-HT and GABA in SCI rats showed a reversal in the impaired cholinergic neurotransmission and reduced the oxidative stress and apoptosis. It also enhanced the expression of cell survival factors in the spinal cord region. In SCI rats treated with 5-HT and GABA, the transplanted BMC expressed NeuN confirming that 5-HT and GABA induced the
differentiation and proliferation of BMC to neurons in the spinal cord. Neurotrophic factors and anti-apoptotic elements in SCI rats treated with 5-HT and GABA along with BMC rendered neuroprotective effects accompanied by improvement in behavioural deficits. This resulted in a significant reversal of altered cholinergic neurotransmission in SCI. The restorative and neuro protective effects of BMC in combination with 5-HT and GABA are of immense therapeutic
significance in the clinical management of SCI.
Description:
Department of Biotechnology, Cochin University of Science and Technology
Kesavankutty,V; Dr.Leelakrishnan, P(Cochin University Of Science And Technology, March 28, 1985)
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Abstract:
In India, film censorship originated with Cinematograph Act 1918 empowering
the Provincial Governments to establish censorial authorities. In 1949, an
amendment provided for a Central Board of Film Censors. In 1952, a new
legislation gave the Central Government enormous powers, making the Board
to function as a department of the Central Government. The Government had
control over the Board with the mechanism of issuing 'directions' to the censors
and laying down censorship rules. The legislation did not provide any objective
criteria for censoring films. The 1959 amendment, aimed at curing this defect,
only incorporated the grounds contained in Article 19(2) of the Constitution. Even
after expert studies and a significant decision by the Supreme Court, pointing
out the inadequacy of the existing system, and governmental attempts to bring
reforms by way of fresh directions, appointment of appellate authority and framing
of new rules, the system still warrants radical change. The thesis explores them.
Description:
Department of Law,Cochin University Of Science And Technology
Narendran Nair,R; Dr.Sharma,G S(Cochin University of Science And Technology, February , 1983)
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Abstract:
The present thesis is an attempt by the researcher to Investigate the surface circulation of the Indian Ocean, north of 2095 in relation to the atmospheric circulation over the ocean. The aim is achieved by working out the circu1ation pattern and correlating it with the computed
wind stress and its vorticity. The month wise surface circulation is arrived by drawing the streamlines, using freshand method with superimposed isotache. The zonal ad meridional componance of the wind stress and the curl of the wind stress are computed for each month over 2° latitude longitude quadrangle from the bulk aerodynamic formula, using a computer program. The data for drawing the surface circu1ation and for computing the wind stress and its curl have come from the Dutch Atlas.
Description:
School of marine sciences, Cochin University of Science And Technology
Simily, Joseph; Dr.Kannan, B(Cochin University of Science and Technology, August , 2013)
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Abstract:
Image processing has been a challenging and multidisciplinary research area since decades with continuing improvements in its various branches especially Medical Imaging. The healthcare industry was very much benefited with the advances in Image Processing techniques for the efficient management of large volumes of clinical data. The popularity and growth of Image Processing field attracts researchers from many disciplines including Computer Science and Medical Science due to its applicability to the real world. In the meantime, Computer Science is becoming an important driving force for the further development of Medical Sciences.
The objective of this study is to make use of the basic concepts in Medical Image Processing and develop methods and tools for clinicians’ assistance. This work is motivated from clinical applications of digital mammograms and placental sonograms, and uses real medical images for proposing a method intended to assist radiologists in the diagnostic process. The study consists of two domains of Pattern recognition, Classification and Content Based Retrieval. Mammogram images of breast cancer patients and placental images are used for this study.
Cancer is a disaster to human race. The accuracy in characterizing images using simplified user friendly Computer Aided Diagnosis techniques helps radiologists in detecting cancers at an early stage. Breast cancer which accounts for the major cause of cancer death in women can be fully cured if detected at an early stage. Studies relating to placental characteristics and abnormalities are important in foetal monitoring. The diagnostic variability in sonographic examination of placenta can be overlooked by detailed placental texture analysis by focusing on placental grading. The work aims on early breast cancer detection and placental maturity analysis. This dissertation is a stepping stone in combing various application domains of healthcare and technology.
Description:
Department of Computer Applications
Cochin University of Science and Technology