Leeju, P; Dr.Mohammed Yusuff,K K(Cochin University of Science & Technology, April , 2011)
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Abstract:
In this thesis we report the synthsis and characterisation of new transition metal complexes of Pd(II),Cu(II),Ru(II) and Ir(III) of Schiff bases derived from quinoxaline-2-carboxaldehyde/3-hydroxyquinoxaline-2-carboxaldehyde and 5-aminoindazole.6-aminoindazole or 8-aminoquinoline.The complexes have been characterised by spectral and analytical data.Pd(II) and Cu(II) form square planar complexes and Ru(III) and Ir(III) form ctahedral complexes with these Schiff bases.The DNA binding properties of theses synthesised complexes have been studied by various methods including electronic absoption spectroscopy,cyclic voltammetry,different pulse voltammetry and circular dichroism spectra were used.Gel electrophoresis experiments were also performed to investigate the DNA cleavage of theses complexes.Furthermore Ru(III) and Ir(III) complexes find application as oxidation and hydogenation catalsts. The studies on catalytic activities has been presented.The metal complexes presented in this thesis assure significance as they contribute to the development of new DNA binding agents and antibacterial and anticancer drugs.
Description:
Dept.of Applied Chemistry,Cochin University of Science and Technology
Xavier, K O; Dr.Mohammed Yusuff,K K(Cochin University of Science & Technology, June , 2000)
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Abstract:
Zeolite encapsulated transition metal complexes have received wide attention as an
effective heterogenized system that combines the tremendous activity of the metal
complexes and the attractive features of the zeolite structure. Zeolite encapsulated
complexes offer a bright future for attempts to replace homogeneous systems retaining
its catalytic activity and minimizing the technical problems. especially for the partial
oxidation of organic compounds. Studies on some zeolite encapsulated transition metal
complexes are presented in this thesis. The ligands selected are technically important in a
bio-mimetic or structural perspective. Attempts have been made in this study to
investigate the composition, structure and stability of encapsulated complexes using
available techniques. The catalytic activity of encapsulated complexes was evaluated for
the oxidation of some organic compounds. The recycling ability of the catalyst as a
result of the encapsulation was also studied.Our studies on Cu-Cr/Al2O3, a typical metal oxide catalyst. illustrate the use of
design techniques to modify the properties of such conventional catalysts. The catalytic
activity of this catalyst for the oxidation of carbon monoxide was measured. The effect
of additives like Ce02 or Ti02 on the activity and stability of this system was also
investigated. The additive is potent to improve the activity and stability ofthe catalyst so
as to be more effective in commercial usage.
Description:
Department of Chemical Oceanography,
Cochin University of Science
and Technology