Roji, Kunnath J; Dr.Prathapachandra Kurup,M R(Cochin University Of Science And Technology, August 5, 2013)
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Abstract:
The work embodied in this thesis was carried out by the author in the Department of Applied Chemistry, CUSAT, Kochi, during the period 2008-2013. The thesis brings to light, our attempts to evaluate the coordination behavior of some compounds of interest. The biological activities of semicarbazones and their metal complexes have been an active area of research during the past years because of their significant role in naturally occurring biological systems. Tridentate NNO and ONO semicarbazone systems formed from heterocyclic and aromatic carbonyl compounds and their transition metal complexes are well-authenticated compounds in this field and their synthesis, crystal structures and spectral studies are well desirable. Hence, we decided to develop a research program aimed at the syntheses, crystal structures and spectral studies of copper complexes with halides and pseudohalides. In addition to single crystal X-ray diffraction studies, various physico-chemical methods of analysis were also used for the characterization of the complexes
Description:
Department Of Applied Chemistry
Cochin University Of Science And Technology
Leji, Latheef; Dr.Prathapachandra Kurup,M R(Cochin University of Science & Technology, September , 2007)
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Abstract:
The thesis is an introduction to evaluate the coordination behaviour of a few
compounds of our interest. The crucial aim of these investigations was to
synthesize and characterize some transition metal complexes using the ligands
benzaldehyde, 2-hydroxybenzaldehyde and 4-methoxybenzaldehyde N(4)-ring
incorporated thiosemicarbazones.The study involves a brief foreword of the metal
complexes of thiosemicarbazones including their bonding, stereochemistry and
biological activities.The different analytical and spectroscopic techniques used for
the analysis of the ligands and their complexes are discussed.It also deals with the synthesis and spectral characterization of the
thiosemicarbazones and single crystal X-ray diffraction study of one of them.Chapter 3 describes the synthesis, spectral characterization, single crystal X-ray
diffraction studies of copper(ll) complexes with ONS/NS donor
thiosemicarbazones. Chapter 4 deals with the synthesis, spectral characterization
and single crystal X-ray diffraction studies of nickel(II) complexes. Chapter 5
contains the synthesis, structural and spectral characterization of the cobalt(III)
complexes. Chapters 6 and 7 include the synthesis, structural and spectral
characterization of zinc(II) and cadmium(ll) complexes with ONS/NS donor
thiosemicarbazones.
Description:
Department of Applied Chemistry,
Cochin University of Science and Technology
Girish Kumar,K; Karthikeyan, G; Mohanraj, K; Elango, K P(Pleiades, 2006)
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Abstract:
A series of nonelectrolytic lanthanide(III) complexes,
[
ML
2
Cl
3
]
·
2
H
2
O, where M is lanthanum(III),
praseodymium(III), neodymium(III), samarium(III), gadolinium(III), terbium(III), dysprosium(III), and
yttrium(III), containing sulfamethoxazole ligand (L) are prepared. The structure and bonding of the ligand are
studied by elemental analysis, magnetic susceptibility measurements, IR,
1
H NMR,
TG
/
DTA
, X-ray diffraction
studies, and electronic spectra of the complexes. The stereochemistry around the metal ions is a monocapped
trigonal prism in which four of the coordination sites are occupied by two each from two chelating ligands, sulfonyl
oxygen, and nitrogen of the amide group and the remaining three positions are occupied by three chlorines.
The ligand and the new complexes were tested in
vitro to evaluate their activity against the bacteria
Escherichia
coli
and
Staphylococcus
aureus.