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Please use this identifier to cite or link to this item: http://purl.org/purl/659

Title: Age-related and sex-related alterations in f3-adrenergic receptors in different regions of rat brain
Authors: Paulose,C S
Kanungo, M S
Keywords: aging
Propranolol
B-adrenergic receptor; aging
Dihydroalprenolol
Norepinephrine
Issue Date: 21-Apr-1982
Publisher: Department of Biotecnology
Abstract: The binding of (-)[ 3H ]dihydroalprenolol , an antagonist of norepinephrine , to $-adrenergic receptors in different regions of the brain of male and female rats of various ages was measured . The binding to the synaptosomal fraction of corpus striatum , hypothalamus, cerebral cortex, cerebellum and the brainstems shows a significant decrease in the binding in old rats of both sexes . Only in the female corpus striatal region, the binding in the adult and the old is the same . In the case of females, the highest binding is seen in the young. In the male, an increase in binding occurs up to adulthood , after which it declines, suggesting a definite sex-related difference in the Q-adrenergic receptor.
URI: http://dyuthi.cusat.ac.in/purl/659
Appears in Collections:Dr.C S Paulose

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