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Please use this identifier to cite or link to this item: http://purl.org/purl/4056

Title: Establishment of Shrimp Cell Lines: Perception and Orientation
Authors: Bright Singh, I S
Jose, Seena
Jayesh, P
Keywords: Shrimp cell culture
Culture medium
Cell line
Issue Date: 14-Aug-2012
Publisher: Springer
Abstract: Development of continuous shrimp cell lines for effective investigation on shrimp viruses remains elusive with an arduous history of over 25 years. Despite presenting challenges to researchers in developing a cell line, the billion dollar aquaculture industry is under viral threat. Advances in molecular biology and various gene transfer technologies for immortalization of cells have resulted in the development of hundreds of cell lines from insects and mammals, but yet not a single cell line has been developed from shrimp and other marine invertebrates. Though improved growth and longevity of shrimp cells in vitro could be achieved by using modified growth media this did not make any leap to spontaneous transformation; probably due to the fact that shrimp cells inhibited neoplastic transformations. Oncogenic induction and immortalization are considered as the possible ways, and an exclusive medium for shrimp cell culture and an appropriate mode of transformation are crucial. In this review status of shrimp cell line development and its future orientation are discussed
Description: Indian J. Virol. (July–September 2012) 23(2):244–251 DOI 10.1007/s13337-012-0089-9
URI: http://dyuthi.cusat.ac.in/purl/4056
Appears in Collections:Bright Singh I S

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