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Please use this identifier to cite or link to this item: http://purl.org/purl/3717

Title: Isolation, purification, characterization and application of proteinaceous protease inhibitor from marine bacterium Pseudomonas mendocina BTMW 301
Authors: Sapna, K
Dr.Elyas, K K
Keywords: Proteases
Protease inhibitors
Competitive inhibition
Exosite binding
Therapeutic agents Proteinaceous inhibitors
Issue Date: Mar-2013
Publisher: Cochin University of Science And Technology
Abstract: The microorganisms are recognized as important sources of protease inhibitors which are valuable in the fields of medicine, agriculture and biotechnology. The protease inhibitors of microbial origin are found to be versatile in their structure and mode of inhibition that vary from those of other sources. Although surplus of low molecular weight non-protein protease inhibitors from microorganisms have been reported, there is a dearth of reports on proteinaceous protease inhibitors. The search for new metabolites from marine organisms has resulted in the isolation of more or less 10,000 metabolites (Fuesetani and Fuesetani, 2000) many of which are gifted with pharmacodynamic properties. The existence of marine microorganisms was reported earlier, and they were found to be metabolically and physiologically dissimilar from terrestrial microorganisms. Marine microorganisms have potential as important new sources of enzyme inhibitors and consequently a detailed study of new marine microbial inhibitors will provide the basis for future research (Imada, 2004).
Description: Department of Biotechnology, Cochin University of Science and Technology
URI: http://dyuthi.cusat.ac.in/purl/3717
Appears in Collections:Faculty of Technology

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