Neuroendocrinology of Pyridoxine Deficiency

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Neuroendocrinology of Pyridoxine Deficiency

Show simple item record Dakshinamurti,K Paulose,C S Viswanathan,M Siow,Y L 2008-08-05T08:24:42Z 2008-08-05T08:24:42Z 1988
dc.description.abstract Veuruenducrim lri v j p .rim, deficienc:v. NEUROSCI BIOBEHAV REV 12(3/4) 189-193. 1988.- Dihydroxyphenylalanine decarboxvlase and 5-hydroxytryptophan decarboxvlase respectively have high and low affinities for pyridoxal phosphate. In the pyridoxinedeficient animal. hypothalamic serotonin content is significantly reduced without any change in catecholamine levels. Hypothalamic neurotransmitters affect the hvpothalamo-pituitary-end organ axes. Specifically, the decrease in hypothalamic serotonin in the pyridoxine-deficient rat results in tertiary hypothyroidism. In addition. pineal function is affected in deficient animals due to decreased synthesis of melatonin. en_US
dc.language.iso en en_US
dc.publisher Department of Biotechnology en_US
dc.subject Decarboxylase en_US
dc.subject Serotonin en_US
dc.subject Melatonin en_US
dc.subject Hypothyroidism en_US
dc.title Neuroendocrinology of Pyridoxine Deficiency en_US
dc.type Working Paper en_US

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