Fabrication of Electrochemical Sensors for Pharmaceutical Analysis

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Fabrication of Electrochemical Sensors for Pharmaceutical Analysis

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dc.contributor.author Sareena, John
dc.contributor.author Dr. Girish Kumar, K
dc.date.accessioned 2012-02-14T10:47:02Z
dc.date.available 2012-02-14T10:47:02Z
dc.date.issued 2007-12
dc.identifier.uri http://dyuthi.cusat.ac.in/purl/2752
dc.description Department of Applied Chemistry, Cochin University of Science and Technology en_US
dc.description.abstract Potentiometric chemical sensors,an important class of electro-chemical sensors are widely used in pharmaceutical analysis because of its inherent advantages.The present study was aimed at fabrication of potentiometric sensors for the drugs mebendazole,pefloxacin,ambroxol,sildenafil citrate,dextro-methorphan and tetracycline.A total of 18 sensors have been developed for the determination of theses drugs.The major step in the fabrication of the sensor was the preparation of the ion association.Two types of sensors viz:PVC membrane sensor and carbon paste electode (CPE) were fabricated.The response characteristics of the different sensors fabricated were studied.Various response parameters studied include response time,selectivity and the effect of pH.The developed sensors were also employed for the determination of the drugs in pharmaceutical formulations and also for the recovery of the drug from urine samples.The selectivity studies reveal that the developed sensors are highly selective to the drug even in prescence of foreign ions. en_US
dc.language.iso en en_US
dc.publisher Cochin University of Science and Technology en_US
dc.subject Electrochemical Sensors en_US
dc.subject Pharmaceuticals en_US
dc.subject Potentiometric Sensors en_US
dc.subject Mebendazole en_US
dc.subject Pefloxacin en_US
dc.subject Ambroxol en_US
dc.subject Sildenafil citrate en_US
dc.subject Dextromethorphan en_US
dc.subject Tetracycline en_US
dc.title Fabrication of Electrochemical Sensors for Pharmaceutical Analysis en_US
dc.type Thesis en_US


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