New Spectrophotometric Methods for the Determination of Nimesulide

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New Spectrophotometric Methods for the Determination of Nimesulide

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dc.contributor.author Girish Kumar, K
dc.contributor.author Chowdary, K P R
dc.contributor.author Devala Rao, G
dc.date.accessioned 2010-11-19T09:16:23Z
dc.date.available 2010-11-19T09:16:23Z
dc.date.issued 1999-01-08
dc.identifier.citation KVSR Siddhartha College of Pharmaceutical Sciences en_US
dc.identifier.other Indian J.Pharm.Sci.1999, 61 (2) 86-89
dc.identifier.uri http://dyuthi.cusat.ac.in/xmlui/purl/1926
dc.description.abstract Two simple and sensitive spectrophotometric methods (A and B)in the visible region have been developed for the determination of nimesulide in bulk and in dosage forms.Method A is based on the reaction of reduced nimesulide with nitrous acid followed by its coupling with phloroglucinol to yield an yellow colored azo dye with an absorption maximum of 400 nm and method B is based on the reaction of reduced nimesulide with p-dimethylamino benzaldehyde(PDAB) to form an yellow colored chromogen wiht an absorption maximum of 415 nm.When pharmaceutical preparations (Tablets and suspension) were analysed, the results obtained by the proposed methods are in good agreement with the labelled amounts and are comparable with the results obtained by a reported method.recovery in both the method is 98-101 %. en_US
dc.language.iso en en_US
dc.publisher Indian Journal Of Pharmaceutical Sciences en_US
dc.subject Spectrophotometer en_US
dc.subject Nimesulide en_US
dc.subject Beer's Law en_US
dc.subject Chemistry en_US
dc.title New Spectrophotometric Methods for the Determination of Nimesulide en_US
dc.type Working Paper en_US


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