Microwave dielectric ceramics based on GdTiNb,-,.Ta,O6 and Sml _.,Y,TiTa06 have been prepared by conventional solid state
method . The GdTiTaO6 and SmTiTaO6 have aeschenite structure with positive rr and GdTiNbO6 and YTiTaO6 have euxenite
structure with negative rr. The rr of the ceramics has been tuned by preparing solid solution phases between the aeschynites and
euxenites for a possible zero rr material . It is observed that GdTiNbt_YTa.,O6 undergoes a phase transition from aeschynite to
euxenite when x=0.75 and in Sml-,YxTiTa06 for x= 0.73. The microwave dielectric properties change abruptly near the transition
region . The rr value approaches zero near the phase transition region while the samples have poor sinterability and poor quality
factor . The unloaded quality factor, dielectric constant and the sign of rr of the solid solution phases are found to depend on the
average ionic radius of the rare earth ion in RE ,-5RE',TiTaO6. The boundary of the euxenite-aeschynite phase transition occurs at
an average ( RE) ionic radius of 0.915 A in Sm,_, Y,.TiTaO6 solid solution phases
Sheelu,Varghese; Bake,Shameena; Lakshmy,P S; Biju,M P; Eswar Shankar,P N; Paulose,C S; Oommen,V Oommen(Department of Bio Technology, August 27, 2001)
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Abstract:
The effects of feeding of 6-propyllhiouracil (6-I'fU) and potyunsaturatcd fatty acids (I'UFA) independently and ill
combination and administration (ip) of a single close of Iriiodothyronine (I',) (2.51ig/IOOg body wl) along with feeding of 6-
PTU and PUFA were studied in cal brain. Dopamine (DA), 5-hydroxytryplophan (5-IIl'I'), serolouin (5-Ill), 5-hydioxy indole
acetic acid (5-111AA), norepinephrine (NF) :uul ceinephrinn (I?I'l) contenls were assayed in the hypothalannls and ccrc
bral cortex regions. It was found that 6-P"l'U Iccding resulted in decrease in dopamine, 5-III', 5 II I I' and 5 IIiAA in both
regions. In animals fed wills PUFA followed by adnliuislralion of T,. the I)A level was found normal.
Balarama Kaimal,S; Gireesh,G; Paulose,C S(Department of Biotechnology, January 4, 2007)
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Abstract:
Gamma amino outyric acid is a major
inhibitory neurotrarsr titter in the central nervous
system. In the preset study sv, Have investigate(' the
alteration of GABA receptor, In t he hrain stem of rats
during pancreatic regeneration. Three groups of rats
were used for the study: sham operated, 72 It and
7 days partially pancreatectonnsea. GABA was (juan-
(ified by [H]GABA receptor iispiacement method.
GABA receptor kin: 10, pat at i et•ers were studied by
using the binding of F'.](iAhA as ligand to the Triton
X-100 treated me,i1,;-:mes a1,J displacement with
unlabelled GABA. GhRA,v receptor activity was
studied by using the [` -1 h3cuculline and displacement
with unlabellecV euculline. ;.\13A content significantly
decreased (1' < (1.(101 ) it, 0-e brain stern during
the regeneration of pancreas. 'I hl, high affinity (IAI3A
receptor binding sho?:ed it sigii'f cant decrease in 131„.,\
(P < 11.01) and K,I 1).05) n 72 h and 7 days after
partial pancreatee 'timv. ";:flhicuculline hin(Iing
showed it signih eat, 'le ( r(, :,e in /Jn1,s and K,I
(P < 0.001) in 72 h pa^.rcreaw,, mised rats when compared
with sham wt--tt' as P,n and K,I reversed to
near sham after 7 da,s of pancreatectomv. The results
sugge,) that GAB A throur,r; ('GABA receptors in
brain Atcem has a regulatory uie during active regeneration
of pancreas which will have inunense clinical
significance in the treatment of cliahetcs.
Gopalapillai,Indulal; Ivan,Gutman; Vijayakumar,Ambat(Department of Mathematics, August 25, 2007)
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Abstract:
The D-eigenvalues of a graph G are the eigenvalues of its distance matrix D, and the
D-energy ED(G) is the sum of the absolute values of its D-eigenvalues. Two graphs are
said to be D-equienergetic if they have the same D-energy. In this note we obtain bounds
for the distance spectral radius and D-energy of graphs of diameter 2. Pairs of equiregular
D-equienergetic graphs of diameter 2, on p = 3t + 1 vertices are also constructed.
Sulaiman,Pyroja; Binoy,Joseph; Paulose,C S(Department of Biotechnology, December 5, 2006)
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Abstract:
In the present study, serotonin 2C (5-HT2c) receptor binding parameters in the brainstem and cerebral cortex were investigated during
liver generation after partial hepatectomy (PH) and N-nitrosodiethylamine (NDEA) induced hepatic neoplasia in male Wistar rats. The
serotonin content increased significantly (p<0.01) in the cerebral cortex after PH and in NDEA induced hepatic neoplasia. Brain stem
serotonin content increased significantly (p<0.05) after PH and (p<0.001) in NDEA induced hepatic neoplasia. The number and affinity of
the 5-HT2c receptors in the crude synaptic membrane preparations of the brain stem showed a significant (p<0.001) increase after PH and in
NDEA induced hepatic neoplasia. The number and affinity of 5-HT2c receptors increased significantly (p<0.001) in NDEA induced hepatic
neoplasia in the crude synaptic membrane preparations of the cerebral cortex. There was a significant (p<0.01) increase in plasma
norepinephrine in PH and (p<0.001) in NDEA induced hepatic neoplasia, indicating sympathetic stimulation. Thus, our results suggest that
during active hepatocyte proliferation 5-HT2c receptor in the brain stem and cerebral cortex are up-regulated which in turn induce hepatocyte
proliferation mediated through sympathetic stimulation.
Indulal,G; Vijayakumar,Ambat(Department of Mathematics, 2002)
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Abstract:
Two graphs G and H are Turker equivalent if they have the same set of Turker angles.
In this paper some Turker equivalent family of graphs are obtained.
Jackson,James; Paulose,C S(Department of Biotechnology, May 1, 2000)
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Abstract:
5-HT2A receptor binding parameters were studied in the cerebral cortex and brain stem of
control, diabetic, insulin, insulin + tryptophan and tr3yptophan treated streptozotocin diabetic
rats. Scatchard analysis using selective antagonist, [-H](±)2,3-dimethoxyphenyl-l-[2-(4-piperidine)-
methanol] ([3H]MDL100907) in cerebral cortex of diabetic rats showed a significant
decrease in dissociation constant (Kd) without any change in maximal binding (Bm). Competition
binding studies in cerebral cortex using ketanserin against [3H]MDL100907 showed
the appearance of an additional site in the low affinity region during diabetes. In the brain
stem, Scatchard analysis showed a significant increase in Bmax and Kd. Displacement studies
showed a shift in the receptor affinity towards a low affinity state. All these altered parameters
in diabetes were reversed to control level by insulin, insulin + tryptophan and tryptophan
treatments. Tryptophan treatment is suggested to reverse the altered 5-HT2Abinding and
blood glucose level to control status by increasing the brain 5-HT content.
Mridula,S; Sreedevi,Menon K; Mohanan,K; Bijumon,P V(Microwave and Optical Technology Letters, February 20, 2004)
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Abstract:
The radiation characteristics of a microstrip-line-excited rectangular dielectric resonator antenna (DRA) are studied experimentally.The radiation charactristics and excitation of different modes are highly influenced by the orientation of the DR,feed line parameters ,and finite size of the ground plane