The effect of various processing parameters, such as nip gap, friction ratio
and roll temperature, on the tensile properties of short Kevlar aramid
fibre-thermoplastic polyurethane composite has been investigated and the tensile
and tear fracture surfaces have been characterised using a scanning electron microscope.
A nip gap of 0.45 mm, a friction ratio of 1.15 and a roll temperature of 62°C
was found to give optimum mechanical properties. Scanning electron microscopy
study revealed a higher extent of fibre orientation in the milling direction in the
above condition.
Pius S,Padayatti; Paulose,C S(Department of Biotechnolgy, April 2, 1999)
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Abstract:
The brain stems (13S) of streptozotocin (STZ)-diabetic rats were studied lo see the changes in
neurotransmitter content and their receptor regulation. The norepinephrine (NE) content
determined in the diabetic brain stems did ^ control. an E showed la
while
PI turnover
hri
content increased significantly compared N^r eNveFa o the recep
significant increase. The alpha2 adrenergic receptor
IneP utisoulinntreat d ratsetheNE contentt dec^ sled
was significantly reduced during diabetes. in
versedcto reanorm
sed
ulcrea e tK
reatment
the
state.
while EPI content remained increased as in die diabetic
B,, for a]pha2 adrenergic receptors slw^nificantly while
Unlabelled clonidine inhibited [31-I]NE binding in BS of control, diabetic and insulin treated
ulations bindi
diabetic rats showed that alpha2 adrenergicre^ punks cojnidiabetic animal the ligand bound
sites with Hill slopes significantly away from unity.
weaker to the low affinity site than in controls. Insulin treatment reversed[ this allumbmn to
control levels. The displacement analysis using (-)-epinephrine age in
control and diabetic animals revealed two populations of receptor affinidtyo=tat ss. In control
animals, when GTP analogue added with epinephrine, the curve nagnlde caofnfitnroit yS
model; but in the diabetic BS this effect `not
aobserved. In
bintact
oth the diabetic
data thus showlthat
the effects of monovalent cations on affinity
alphaz adrenergic receptors have a reduced affinity v
due
in stem ialtered Itscppeomson(5-
regulation. The serotonin (5-HT) coat
hydroxy) tryptophan (5-HTP) showed an increase and its breakdown metabolite (5-hydroxy)
indoleacetic acid (5-I{IAA) showed a significant decrease. This showed that in serotonergic
which l
nerves there is a disturbance in both synthetic and breankduomwnbers pretma'med ana
increased 5-HT. The high affinity serotonin receptor um ese serotonerg
decrease in the receptor affinity. The insulin ^treatmentsturtiy showsha decreased serotonergic
receptor kinetic parameters to control level.
receptor function. These changes in adrenergic and serotonergic receptor function were
suggested to be important in insulin function during STZ diabetes.
Ponnachan,P T C; Paulose,C S; Panikkar,K R(Department of Biotechnology, 1991)
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Abstract:
Alloxan induced diabetic animal model was
sed to evaluate the potential antidiabetic effect of
ie aqueous leaf extract of Aegle marmelose. Insuinjection
and oral treatment of Aegle marmelose
of extract to the alloxan induced rats maintained
;e animal weight near to the control rats whereas
,,ere was a significant decrease in weight in alloxan
•duced rats. Insulin injection and oral treatment
the leaf extract reversed the decrease of protein
)ntent in all the organs studied except the pancas.
Glucose level was maintained near to the co-
:rol levels in the insulin injected and leaf extract
Bated alloxan diabetic rats. A significant increased
ucose tolerance was observed in animals orally
ven the leaf extract prior to the experiment. The
suits indicate that there is an increased utilization
glucose in the Aegle marmelose leaf extract treed
rats.
Ponnachan, P T C; Paulose, C S; Panikkar, K R(Department of Biotechnology, April , 1993)
[+]
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Abstract:
Alloxan induced animal model was used to evaluate the potential antidiabetic effect of A . marmelose leaf
extract. The diabetic animals were given insulin injection and another group A . marmelose leaf extract orally.
It maintained the weight of the animals near to the control rats but a significant decrease in weight was noted it
diabetic animals without any treatment . The blood elucose level in 'treated animals were near to that of control
ones. Also a significantly increased glucose tolerance was observed in animals orally given the leaf extract
prior to the experiment . A significant decrease in liver glycogen ( 1.24 -.07 s!/ 100 g of wet tissue) was observed
in diabetic rats which was brought to almost the normal level (I.84- . 14 g; 100 g) with Icaf extract treatment.
Blood urea and serum cholesterol increased ( 62.66 - 3.50 and 192.67± 13.64 mg' dl) significantly in alloxxan
diabetic rats . The leaf extract treatment decreased the blood urea and serum . cholesterol (37.83 - 3.97 and
99?0±8.43 mg/dl ) to that of control ones . A similar effect was seen with insulin treatment . The results
indicate that the active principle in .4. marmelose leaf extract has similar hypoglycaemic activity to insulin
treatment.
Jackson,James; Pius S,Padayatti; Thomas,Paul; Paulose,C S(Department of Biotechnology, December 13, 1996)
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Abstract:
In the present study we assessed plasma and platelet
monoamine content using high performance liquid
chromatography (HPLC). The study included 22 subjects
consisting of 12 freshly-detected male diabetic
patients and 10 age and sex-matched healthy controls.
The same parameters were measured in streptozotocin
-induced diabetic rat models consisting of
controls , diabetic and insulin - treated diabetic rats.
The platelet counts were significantly reduced
(P < 0.05) in rat models as well as human diabetic
samples. The plasma norepinephrine (NE) and epinephrine
(EPI) concentrations were significantly increased
(P < 0.05). The platelet showed a significant
increase (P < 0.01) in NE, EPI and serotonin content.
Increase in the plasma and platelet content of neurotransmitters
may be due to increased sympathetic
function, which is an adaptation for the decreased
platelet count observed in our study . The results indicate
that changes in the neurotransmitter content
of the platelet may be a good index to assess the neurotransmitter
status in pathological condition such as
diabetes mellitus.
New dielectric ceramics with formula BaTi3Nb4, O„ and Ba6Til4Nbz039 have been prepared and characterized. BaTi3Nba017 was densified to 92% of TD after firing at 1310 oC for 4 h. However, Ba6Ti 1 4Nb2O39 fired under optimized conditions (1260 ` C for 4 h) showed only 85% TD together with secondary phase. The crystal system of both of the compositions is orthorhombic
Stephen,D S; Mathew,T; Jose,K A; Aanandan,C K; Mohanan,P; K G Nair(Department of Electronics, February , 1993)
[+]
[-]
Abstract:
Simultaneous elimination of specular reflection and backscattered
power from a plane metallic surface by simulated
corrugated surfaces of constant period and variable strip
width for TM polarisation is reported. This new configuration
offers almost a ten-fold frequency bandwidth compared
with a regularly spaced strip grating of the same size.