Sinu, C R; Vijay, Nair, G; Radhakrishnan, K V(Cochin University of Science And Technology, November 22, 2014)
[+]
[-]
Abstract:
The thesis entitled “Exploration of Novel Organic Reactions Catalyzed by
Nucleophilic Heterocyclic Carbenes (NHCs)” embodies the results of the
investigations carried out to explore the synthetic potential of N–heterocyclic carbenes
(NHCs) as organocatalyst towards various electrophiles for the synthesis of heterocyclic
and carbocyclic systems. Recent investigations in the generation of homoenolates by the
addition of NHCs to conjugated aldehydes have made it possible to study the reactivity of
this unique three carbon synthon.