Aniladevi Kunjamma, K P; Dr. Babu, Philip(Cochin University of Science and Technology, April , 2008)
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Abstract:
Man uses a variety of synthetic material for his comfortable materialistic
life. Thus human interactions may become harmful for various terrestrial and aquatic
lives. This is by contaminating their habitat and by becoming a threat to organisms
itself. Thus the application and dispersal of several organic pollutants can lead to the
development of several mutated forms of the species when exposed to sublethal
concentrations of the pollutants. Otherwise, a decrease in number or extinction of
these exposed species from earth's face may happen. Pesticides, we use for the
benefit of crop yield, but its persistence may become havoc to non-target organism.
Pesticides reaching a reservoir can subsequently enter the higher trophic levels.
Organophosphorus compounds have replaced all other pesticides, due to its acute
toxicity and non-persistent nature.Hence the present study has concentrated on the toxicity of the largest
market-selling and multipurpose pesticide, chlorpyrifos on the commonly edible
aquatic organism, fish. The euryhaline cichlid Oreochromis mossambicus was
selected as animal model. The study has concentrated on investigating biochemical
parameters like tissue-specific enzymes, antioxidant and lipid-peroxidation
parameters, haematological and histological observations and pesticide residue
analysis.Major findings of this work have indicated the possibility of aquatic toxicity
to the fish on exposure to the insecticide chlorpyrifos. The insecticide was found as
effective to induce structural alteration, depletion in protein content, decrease in
different metabolic enzyme levels and to progress lipid peroxidation on a prolonged
exposure of 21 days. The ion-transport mechanism was found to be adversely
affected. Electrophoretic analysis revealed the disappearance of several protein bands
after 21days of exposure to chlorpyrifos. Residue, analysis by gas chromatography
explored the levels of chlorpyrifos retaining on the edible tissue portions during
exposure period of 21days and also on a recovery period of 10 days.
Description:
Department of Marine Biology, Microbiology and Biochemistry, Cochin
University of Science and Technology.
Shiny, K S; Dr. Anandan, R(Cochin University of Science and Technology, February , 2007)
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Abstract:
The present study indicate that prior administration of
taurine is effective in minimizing all the deleterious effects induced by isoproterenol,
thereby justifying its use as a potent cytoprotective agent. The overall cardioprotective
effect of taurine is probably related to its antioxidant property evidenced by its ability to
reduce lipid peroxidation and to maintain the activities of free radical enzymes and nonenzymatic
antioxidants, its membrane stabilizing action and to its hypolipidemic property.
Description:
Dept.of Marine Biology,Microbiology and Biochemistry,Cochin University of Science and Technology