Paulose,C S; Dakshinamurti,K(Department of Biotechnology, April 24, 1984)
[+]
[-]
Abstract:
The high-affinity of [3H]y-aminobutyric acid (GABA) to GABAA receptors and [3H]baclofen to
GABAB receptors were studied in the cerebellum of pyridoxine-deficient rats and compared to
pyridoxine-supplemented controls. There was a significant increase in the maximal binding ( Bmax) of both
GABAA and GABAB receptors with no significant difference in their binding affinities (Kd). The changes
observed suggest a supersensitivity of GABAA and GABAB receptors which seems to correlate negatively
with the concentration of GABA in the cerebellum of pyridoxine-deficient rats.
Paulose,C S; Dakshinamurti,K(Department of Biotechnology, December 19, 1984)
[+]
[-]
Abstract:
The high-affinity bindings of [3H]-5-hydroxytryptamine to serotonin S-1 receptors,
[3H]-ketanserin to serotonin S-2 receptors in the cerebral cortex, [3H]-
fluphenazine to dopamine D-1 receptors, and [3H]-spiroperidol to dopamine D-2
receptors in the corpus striatum were studied in pyridoxine-deficient rats and
compared to pyridoxine-supplemented controls. There was a significant increase
in the maximal binding (Bmax) of serotonin S-1 and S-2 receptors with a significant
decrease in their binding affinities (Kd). However, there were no significant
changes either in the maximal binding or binding affinity of striatal dopamine D-
1 and D-2 receptors. Receptor sensitivity seems to correlate negatively with the
corresponding neurotransmitter concentrations in the pyridoxine-deficient rats.
David Peter,S; Paulose Jacob,K(Cochin University of Science and Technology, August , 2006)
[+]
[-]
Abstract:
The present study shows design and development of a performance evaluation prototype for IT organizations in the context of outsourcing. The main objective of this research is to help an IT organization in the context of outsourcing to realize its current standing, so it can take corrective steps where ever necessary and strive for continuous improvement. Service level management (SLM) process plays a crucial role in controlling the quality provision for IT service. Out sourcing is the process of entrusting the responsibility of providing certain goods and services to an external party. We have tried to identify as many as twenty complexities and categorized in to four headings. Complexities associated with contracts and SLAs,SLM process,SLM organization and complexities due to intrinsic characteristics. In this study it is possible to measure the quality of the performance of an IT organization in an outsourcing environment effectively
Paulose,C S; Dakshinamurti,K(Department of Biotechnology, June 12, 1987)
[+]
[-]
Abstract:
Chronic catheterization is illustrated using vascular-access-port model SLA where the port is surgically placed subcutaneously on
the back of the rat. The catheter is tunnelled to the neck and inserted into the jugular vein . Within 24 h rats showed normal blood
pressure and blood samples were collected at intervals with minimal stress to the animals . A comparison of the plasma catecholamine
of blood collected from vascular-access-ports with that obtained from decapitation indicates that there was minimal stress to the rats
when blood was drawn through the vascular-access-port.
Indulal,G; Vijayakumar,A(Department of Mathematics, 2008)
[+]
[-]
Abstract:
Eigenvalue of a graph is the eigenvalue of its adjacency matrix. The energy of a graph is the
sum of the absolute values of its eigenvalues. In this note we obtain analytic expressions for the
energy of two classes of regular graphs.