Biju,M P; Paulose,C S(Department of Biotechnology, September 27, 1997)
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Abstract:
Kinetic parameters of brain glutamate dehydrogenase (GDH) were compared in the brain
stem, cerebellum and cerebral cortex of three weeks and one year old streptozotocin (STZ)
induced four day diabetic rats with respective controls. A single intrafemoral dose of STZ
(60mg/Kg body weight) was administered to induce diabetes in both age groups. After four days
the blood glucose levels showed a significant increase in the diabetic animals of both age groups
compared with the respective controls. The increase in blood glucose was significant in one year
old compared to the three weeks old diabetic rats. The Vmm of the enzyme was decreased in all
the brain regions studied, of the three weeks old diabetic rats without any significant change in
the Km. In the adult the Vmax of GDH was increased in cerebellum and brain stem but was
unchanged in the cerebral cortex. The K. was unchanged in cerebellum and cerebral cortex but
was increased in the brain stem. These results suggest there may be an important regulatory role
of the glutamate pathway in brain neural network disturbances and neuronal degeneration in
diabetes as a function of age.
Eswaran Namboodiri, K K; Sukumaran Nair, M K (Department of Applied Economics)(Department of Applied Economics, Faculty of Social Science, July , 1997)
Cashew kernels have high
nutritive value. Upon exposure
to air kernels turn rancid and
their nutritive value decreases.
From this study it is concluded
that chemical treatment using
antioxidants reduced oxidative
rancidity but failed to prevent
deterioration in organoleptic
characteristics and decrease in
protein and carbohydrate
content of stored kernels.
Tessy,Maliekal T; Sudha,B; Paulose,C S(Department of Biotechnology, February 14, 1997)
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Abstract:
The role of thyroid hormones in DNA synthesis and in the activity of Thymidille
kinase (TK), a key regulatory enzyme of DNA synthesis was studied in proliferating
hepatocytes in vivo. Liver regeneration after partial hepatectomy was used as a
model for controlled cell division in rats having different thyroid status - euthyroid,
hypothyroid and 3,3',5'-triiodo-L-thyronine (T))-heated hypothyroid. Partial
hepatectomy caused a significant elevation of DNA synthesis (p<0.01) in all the three
groups compared to their sham-operated counterparts. Hypothyroid liepatectomised
animals showed significantly lower (p<0.01) level of DNA synthesis than euthyroid
hepatectomised animals. A single subcutaneous close of 1'3 to hypothyroid shamoperated
animals resulted in a significant increase (p<0.01) of DNA synthesis in the
intact liver. 17tis was comparable to the level of DNA synthesis occurring in
regenerating liver of euthyroid animals. In hypothyroid hepatectomised animals, "1'3
showed an additive effect on l)NA synthesis and this group exhibited maximum level
of DNA synthesis (p<0.0I ). Studies of the kinetic parameters of TK show that the
Michelis-Menten constant, (K111) of TK for thymidine was altered by the thyroid
status. K11 increased significantly (p<0.01) in untreated hypothyroid animals when
compared to the euthyroid rats. '13 treatment of hypothyroid animals reversed this
effect and this group showed the lowest value for K111 (p<0.01). Thus our results
indicate that thyroid hormones can influence DNA synthesis during liver regeneration
and they may regulate the activity of enzymes such as 17rymidine kinase which are
important for DNA synthesis and hence cell division.
A bivariate semi-Pareto distribution is introduced
and characterized using geometric minimization.
Autoregressive minification models for bivariate random
vectors with bivariate semi-Pareto and bivariate Pareto
distributions are also discussed. Multivariate
generalizations of the distributions and the processes are briefly indicated.
Anil Kumar, C V; Ramamohan, T R(Computational Materials Science, Unit I Regional Research Laboratory (Council of Scientific and Industrial Research), October , 1997)
V P N Nampoori; Girijavallabhan, C P; Harilal, S S; Riju, C Issac; Bindhu, C V(Journal of Physics D : Applied Physics, January 24, 1997)
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Abstract:
Optical emission studies of C2 molecules in plasma obtained by Nd:YAG
laser ablation of graphite in a helium atmosphere are reported for irradiances in the
range (1–9:2/ x 1010 W cm−2. The characteristics of the spectral emission intensity
from the C2 (Swan band) species have been investigated as functions of the
distance from the target, ambient pressure and laser irradiance. Estimates of
vibrational temperatures of C2 species under various irradiance conditions are
made. Results of measurements performed under different ambient helium gas
pressures are also discussed.
Riju C, Issac; Harilal, S S; Bindhu, C V; Geetha K, Varier; Nampoori, V P N; Vallabhan, C P G(Elsevier, 1997)
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Abstract:
A laser produced plasma from the multielement solid target YBa2Cu3O7 is generated using 1.06 μm, 9 ns pulses from a Q-switched Nd:YAG laser in air at atmospheric pressure. A time resolved analysis of the profile of the 4554.03 Å resonance line emission from Ba II at various laser power densities has been carried out. It has been found that the line has a profile which is strongly self-reversed. It is also observed that at laser power densities equal to or exceeding 1.6×1011 W cm−2, a third peak begins to develop at the centre of the self-reversed profile and this has been interpreted as due to the anisotropic resonance scattering (fluorescence). The number densities of singly ionized barium ions evaluated from the width of the resonance line as a function of time delay with respect to the beginning of the laser pulse give typical values of the order of 1019 cm−3. The higher ion concentrations existing at smaller time delays are seen to decrease rapidly. The Ba II ions in the ground state resonantly absorb the radiation and this absorption is maximum around 120 ns after the laser pulse.
Girijavallabhan, C P; V P N Nampoori; Harilal, S S; Riju, C Issac; Bindhu C V(Journal of Physics D : Applied Physics, January 24, 1997)
[+]
[-]
Abstract:
Optical emission studies of C2 molecules in plasma obtained by Nd:YAG
laser ablation of graphite in a helium atmosphere are reported for irradiances in the
range (1–9:2/ x 1010 W cm−2. The characteristics of the spectral emission intensity
from the C2 (Swan band) species have been investigated as functions of the
distance from the target, ambient pressure and laser irradiance. Estimates of
vibrational temperatures of C2 species under various irradiance conditions are
made. Results of measurements performed under different ambient helium gas
pressures are also discussed.