Paulose,C S; Dakshinamurti,K; Subah,Packer; Newman,L Stephens(Department of Biotechnology, December 8, 1987)
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Abstract:
Pyridoxal phosphate is the coenzyme of various decarboxylases involved in the formation
of monoamine neurotransmitters such as y-aminobutyric acid , serotonin , dopamine, and norepinephrine
. Adult male Sprague-Dawley rats placed on a pyridoxine -deficient diet for 8 weeks showed
significant hypertension compared with pyridoxine -supplemented controls . Hypothalamic contents of
pyridoxal phosphate , y-aminobutyric acid, and serotonin in the pyridoxine - deficient rats were significantly
lower than those in pyridoxine -supplemented controls . Hypertension was associated with
sympathetic stimulation . Treatment of pyridoxine-deficient rats with a single dose of pyridoxine (10
mg/kg body weight) reversed the blood pressure to normal levels within 24 hours, with concomitant
restorations of hypothalamic serotonin and y-aminobutyric acid as well as the return of plasma
norepinephrine and epinephrine to normal levels . Also, pyridoxine treatment reversed the hypothalamic
hypothyroidism observed in pyridoxine -deficient rats . These results indicate an association
between pyridoxine deficiency and sympathetic stimulation leading to hypertension.
Abdul Rasheed, T M; Moosad, K P B; Nampoori, V P N; Sathianandan, K(American Chemical Society, 1987)
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Abstract:
Vibrational overtone spectra of acetophenone and benzaldehyde in the visible and near-infrared regions are studied by the
dual beam thermal lens and the conventional near-infrared absorption techniques. The observed increase in the mechanical
frequency of the aryl CH bond from that of benzene is attributed to the decrease in the aryl CH bond length caused by
the electron-withdrawing property of the substituents. Overtone spectra also demonstrate that acetophenone contains two
types of methyl CH bonds arising from the anisotropic environments created by oxygen lone pair and carbonyl P electrons.
The local-mode parameters of the two types of CH bonds are compared with those of acetone and acetaldehyde. The possible
factors influencing the methyl CH bonds in acetophenone are discussed.
Natural rubber, styrene-butadiene rubber, and polybutadiene
rubber were used to replace part of the butadieneacrylonitrile
rubber in a 70/30 butadiene-acrylonitrile rubber/
poly(vinyl chloride) blend. Such replacement up to 15%
of the total weight of the blend improved the mechanical
properties, while decreasing the cost of the blend. Styrenebutadiene
rubber could replace butadiene-acrylonitrile
rubber up to 30% of the total weight of the blend without
deterioration in the mechanical properties.