Roji, Kunnath J; Dr.Prathapachandra Kurup,M R(Cochin University Of Science And Technology, August 5, 2013)
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Abstract:
The work embodied in this thesis was carried out by the author in the Department of Applied Chemistry, CUSAT, Kochi, during the period 2008-2013. The thesis brings to light, our attempts to evaluate the coordination behavior of some compounds of interest. The biological activities of semicarbazones and their metal complexes have been an active area of research during the past years because of their significant role in naturally occurring biological systems. Tridentate NNO and ONO semicarbazone systems formed from heterocyclic and aromatic carbonyl compounds and their transition metal complexes are well-authenticated compounds in this field and their synthesis, crystal structures and spectral studies are well desirable. Hence, we decided to develop a research program aimed at the syntheses, crystal structures and spectral studies of copper complexes with halides and pseudohalides. In addition to single crystal X-ray diffraction studies, various physico-chemical methods of analysis were also used for the characterization of the complexes
Description:
Department Of Applied Chemistry
Cochin University Of Science And Technology
Manoj, E; Dr.Prathapachandra Kurup,M R(Cochin University of Science and Technology, October , 2007)
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Abstract:
Chemistry occupies a unique middle position in the scientific arena, between
physics and mathematics on the one side and biology, ecology, sociology and
economics on the other [1]. Chemistry is the science of matter and of its
transformations, and life is its highest expression [2]. According to reductionist
thinking biology is reducible into chemistry, chemistry into physics, and ultimately
physics into mathematics. Reductionism implies the ease of understanding one level
in terms of another.The work presented this thesis comprises synthesis and characterization of
suitably substituted thiocarbohydrazone and carbohydrazone ligand building blocks, self-assembled metallosupramolecular square grid complexes as well as some di/multinuclear complexes.
The primary aim was the deliberate syntheses of some novel transition metal framework
complexes, mainly metallosupramolecular coordination square grids by self-assembly
and their physico-chemical characterization. The work presented, however, also
include synthesis and characterization of four mononuclear Ni(II) complexes of two
thiosemicarbazones, which we carried out as a preliminary and supporting study. Based on the present work we would like to conclude that the carbohydrazones, thiocarbohydrazones and their coordination framework complexes of transition metals are promising systems for wide application in science and technology varied from physics to biotechnology. Novel classes of materials and biologically important potential compounds
open up further scope of researches and we hopefully welcome any sort of related research to make this work more valuable.
Seena, E B; Prathapachandra Kurup, M R(Elsevier, 2007)
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Abstract:
Three copper(II) complexes of salicylaldehyde N(4)-phenyl thiosemicarbazone (H2L1) and two copper(II) complexes of N(4)-cyclohexyl thiosemicarbazone (H2L2) have been synthesized and characterized by different physicochemical techniques like magnetic studies and electronic, infrared and EPR spectral studies. The complexes View the MathML source and [(CuL2)2] (4) having dimeric structure. The thiosemicarbazones bind to the metal as dianionic ONS donor ligand in all the complexes, except in the complex [Cu(HL1)2] · H2O (2). In complex 2, the ligand moieties are coordinated as monoanionic (HL−) ones. Two of the complexes [CuL1dmbipy] · H2O (3) and [CuL2dmbipy] (5) have been found to possess the stoichiometry [CuLB], where B = 4,4′-dimethyl-2,2′-bipyridine (dmbipy). The coordination geometry around copper(II) in 5 is trigonal bipyramidal distorted square based pyramidal (TBDSBP), as obtained by X-ray diffraction studies.
Maheswaran Sithambaresan; Dr. M. R. Prathapachandra Kurup(Cochin University of Science and Technology, April 18, 2012)
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Abstract:
The work embodied in this thesis was carried out by the author in the
Department of Applied Chemistry, CUSAT, Kochi, during the period 2009-2012.
The thesis is an introduction to our attempts to evaluate the coordination behavior
of some compounds of our interest. The biological activities of semicarbazones
and their metal complexes have been an active area of research during the past
years because of their significant role in naturally occurring biological systems.
Tridentate NNO and ONO semicarbazone systems formed from heterocyclic and
aromatic carbonyl compounds and their transition metal complexes are wellauthenticated
compounds in this field and their synthesis, crystal structures and
spectral studies are well desirable. Hence, we decided to develop a research
program aimed at the syntheses, crystal structures and spectral studies of new N4-
phenylsemicarbazones derived from 2-formylpyridine and 3-ethoxysalicylaldehyde
and their transition metal complexes and new transition metal complexes of 2-
benzoylpyridine-N4-phenylsemicarbazone. In addition to various physicochemical
methods of analysis, single crystal X-ray diffraction studies were also
used for the characterization of the complexes.