Akhil, K Nair; Dr.Ramaiah,D(Cochin University Of Science And Technology, October 3, 2013)
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Abstract:
Design and study of molecular receptors capable of mimicking
natural processes has found applications in basic research as well as in
the development of potentially useful technologies. Of the various
receptors reported, the cyclophanes are known to encapsulate guest
molecules in their cavity utilizing various non–covalent interactions
resulting in significant changes in their optical properties. This unique
property of the cyclophanes has been widely exploited for the
development of selective and sensitive probes for a variety of guest
molecules including complex biomolecules. Further, the incorporation of
metal centres into these systems added new possibilities for designing
receptors such as the metallocyclophanes and transition metal
complexes, which can target a large variety of Lewis basic functional
groups that act as selective synthetic receptors.
The ligands that form complexes with the metal ions, and are
capable of further binding to Lewis-basic substrates through open
coordination sites present in various biomolecules are particularly
important as biomolecular receptors. In this context, we synthesized a
few anthracene and acridine based metal complexes and novel
metallocyclophanes and have investigated their photophysical and
biomolecular recognition properties.
Description:
Photosciences and Photonics
Chemical Sciences and Technology Division
CSIR-National Institute for Interdisciplinary Science and
Technology (CSIR-NIIST), Trivandrum